De Soto, MO

View of De Soto, MO
Image credit: Paul Sableman / CC BY 2.0
Population
6,527
U.S. Census Population Estimates Program · 2025
Elevation
526 ft
Median Home Value
$160,700
U.S. Census American Community Survey 5-Year · 2024
Median Rent
$809/mo
U.S. Census American Community Survey 5-Year · 2024
Median Income
$52,500
U.S. Census American Community Survey 5-Year · 2024

Explore

De Soto in context.

About De Soto

De Soto is a city in Jefferson County, Missouri, situated along Joachim Creek within the St. Louis metropolitan area. Established in 1803 and named after Spanish explorer Hernando de Soto, the community of approximately 6,470 is supported by a major Union Pacific Railroad facility and served by the De Soto Public School District Seventy-Three for public education.

Top Rating Signals

Highest current ratings for this town.

Loading town details...