De Soto, MS

De Soto is a census-designated place and unincorporated community in Clarke County, Mississippi, United States. The 2020 census counted 274 residents. De Soto was named after Hernando de Soto. De Soto was one of four principle towns established in Clarke County before the American Civil War. In De Soto, history and present-day settings sit close enough to belong to the same local picture. The map tells the story in De Soto, where earlier chapters remain visible in current streets, buildings, and gathering places. De Soto is home to two sawmills. The county is in the zone for Jones College.