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Mayersville, MS

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View of Mayersville, MS
Population
453
U.S. Census Population Estimates Program · 2025
Elevation
106 ft
USGS GNIS community points and 3DEP elevation · GNIS 2026-07-06; USGS 3DEP sampled 2026-07-23
Median Home Value
$104,700
U.S. Census American Community Survey 5-Year · 2024
Median Rent
$238/mo
U.S. Census American Community Survey 5-Year · 2024
Median Income
$15,179
U.S. Census American Community Survey 5-Year · 2024
General Quality
Overall rating out of 100

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OverallBest places in MississippiPopulation rankingHighest population places in MississippiNearest larger communityGreenville, Mississippi34 miles away · 26,530 residents.

About Mayersville

Mayersville sits right along the Mississippi River in rural Issaquena County. As the county seat, it is anchored by the local courthouse and county offices, but daily life here is quiet, unhurried, and closely tied to the surrounding farmland. The nearby levee and river waters shape the local scenery, giving the area a distinct, peaceful feel. For anyone drawn to open Delta skies, outdoor living, and small-town solitude, Mayersville offers a truly relaxed pace.

Top Rating Signals

Highest current ratings for this town.

Rural FitA+99.4ratingRegional Two-Party Electoral BalanceA+99.3ratingLower FEMA County Wildfire Risk IndexA+97.9rating

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