Santee, NE

View of Santee, NE
Population
429
U.S. Census Population Estimates Program · 2025
Elevation
1,245 ft
USGS GNIS community points and 3DEP elevation · GNIS 2026-07-06; USGS 3DEP sampled 2026-07-23
Median Rent
$385/mo
U.S. Census American Community Survey 5-Year · 2024
Median Income
$59,583
U.S. Census American Community Survey 5-Year · 2024
General Quality
Overall rating out of 100

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About Santee

Santee is a small, tight-knit community of around 400 residents located on the Santee Sioux Reservation in northeastern Nebraska. Sitting along the scenic bluffs of the Missouri River in Knox County, it serves as the cultural center for the tribe. Day-to-day life is quiet and unhurried, shaped by deep Dakota heritage, open landscapes, and close connections among neighbors.

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