Chillicothe, TX

Chillicothe is a city in Hardeman County, Texas, United States. The 2020 census counted 549 residents. Chillicothe is on U.S. Route 287, Farm to Market Road 91, Farm to Market Road 2006, and the Fort Worth and Denver and Santa Fe railroads in eastern Hardeman County. Chillicothe was founded in the early 1880s and developed rapidly after the construction of the Fort Worth and Denver City Railway in 1887. Chillicothe's local map joins its older history to the places and landscapes that still shape the town today, all within the wider Texas setting.

The local scoop is how Chillicothe's history still shows up in the places people visit, work, learn, and meet. Chillicothe is located in eastern Hardeman County and US 287 runs through the center of town, leading southeast 16 miles to Vernon and west 13 miles to Quanah, the Hardeman county seat. Wanderers Creek runs past the western side of the city, flowing north towards the Red River at the Oklahoma state line. Chillicothe is home to High School.