Syracuse, MO

Syracuse is a city in Morgan County, Missouri, United States. The 2020 census counted 151 residents. In the middle of the 19th century, the city was the western terminus of the Pacific Railway that reached 108 miles from St. Louis. The current mayor of Syracuse is Duane A. A newcomer can read Syracuse through the overlap of its older landmarks, surrounding geography, and current places. For a newcomer, Syracuse comes into focus through those concrete links among its past, landscape, and current routines. Doyle. In 1859 with the railroad construction to Syracuse, it became the Terminus of The Butterfield Overland Mail Route. The route was designated a national historic trail in 2023.